NIPT Ireland: Non-Invasive NIPD Genetic Veracity
Mourne Scan Clinic are excited to commence a brand-new genetic screening service in collaboration with specialist clinic NIPD Genetics Molecular Laboratories Limited.
NIPD Genetics is a European researched-based biotechnology company. They are currently active in 40 nations across the world. They have developed unique bioinformatics that can overcome the previous technical challenges of similar tests. NIPD Genetics allows for greater accuracy in testing for genetic abnormalities and novel mutations.
NIPD Genetics have a vast testing range including Prenatal tests (New generations NIPT and Comprehensive NIPT with monogenic diseases)
Other screening includes:
- Reproductive Health (carrier screening & infertility screening)
- Postnatal genetic tests (Newborn screening, cardiovascular, metabolic)
- Oncology (Hereditary cancer and tumour profile)
- Whole exome/genome sequence
Mourne Scan Clinic are excited to commence a brand-new genetic screening service in collaboration with specialist clinic NIPD Genetics Molecular Laboratories Limited.
Almost all genetic screening tests available are non-invasive and include fast clinical reporting. All tests are analysed in a state-of-the-art laboratory with CAP/CLIA/ISO/CE-IVD accreditations.
At Mourne Scan Clinic, we will be offering two different types of genetic screening tests.
These tests can be done from 10 weeks of gestation.
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NIPD Genetics Veracity Test
New generation non-invasive prenatal test (NIPT) (also known as ‘Panorama Test’) -
NIPT Genetic VERAgene Test
Comprehensive non-invasive prenatal test (NIPT)
If you are unsure of which test you require, please contact the clinic for more information
Telephone: 02830263712
Email: lisamournescanclinic@gmail.com
Email: louisemournescanclinic@gmail.com
Frequently Asked Questions
NIPD Genetic Veracity Test:
This is described by NIPD Genetics as a ‘new generation NIPT’ (similar to ‘Panorama Test’)
What is NIPT? (non-invasive prenatal test)
During pregnancy, cell-free fetal DNA travels form the placenta and circulates with the mother’s blood along with her own cell-free DNA.
This discovery led to the development of non-invasive prenatal tests (NIPT)
Non-invasive prenatal screening is a test taken by a pregnant woman to screen for genetic conditions of the baby before birth.
Non-invasive prenatal screening analyses cell-free DNA in the mother’s blood to identify these conditions.
Veracity is a new generation non-invasive prenatal test (NIPT). This test can be done from 10 weeks of gestation.
What are genetics conditions?
Genetic conditions are caused by unwanted variations in the genome that occur during conception.
There are two different variations of genetic conditions identified with the Veracity test.
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Aneuploidies
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These are genetic conditions that occurs when a chromosome has
• an extra copy (trisomy) • missing a copy (monosomy) |
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Microdeletions
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These are genetic conditions that are caused by a small deletion in a particular region of a chromosome.
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What genetic conditions can be screened by Veracity?
1st Level
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Autosomal Aneuploidies
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Down Syndrome (also known as Trisomy 21)
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Edwards Syndrome (also known as Trisomy 18)
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Patau Syndrome (also known as Trisomy 13)
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2nd Level
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Down Syndrome (also known as Trisomy 21)
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Edwards Syndrome (also known as Trisomy 18)
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Patau Syndrome (also known as Trisomy 13)
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Turner Syndrome (also known as Monosomy X)
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Triple X Syndrome (also known as Trisomy X)
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Klinefelter Syndrome (also known as XXY)
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Jacob’s Syndrome (also known as (XYY)
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XXYY Syndrome
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Microdeletions
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Digeorge Syndrome
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1P36 Deletion Syndrome
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Smith-Magenis Syndrome
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Wolf- Hirchhorn Syndrome
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Gender determination can also be done if required.
How does Veracity (new generation NIPT) work?
During pregnancy, fetal DNA releases form the placenta to the mother’s blood stream and circulates along with her own DNA.
Veracity is a new generation non-invasive prenatal test that will accurately measure the fetal cell free DNA (cffDNA) in the mother’s blood to test for fetal aneuploidies.
During your appointment:
• You will be scanned to date your pregnancy (EDD)
• A nurse or sonographer will collect a sample of blood from the mother’s arm during their appointment at Mourne Scan Clinic.
This sample will then be sent to the state-of-the-art laboratory for analysis. New generation, analytic and bioinformatic technologies are used.
Results will then be provided to the clinic in 10 working day
Mourne Scan Clinic will provide the patient with a follow-up appointment date to provide results.
When can I take the Veracity test (new generation NIPT)?
When it comes to your baby’s health, accuracy is crucial. One of the advantages of Veracity is that you can take the test as early as the 10th week of pregnancy.
The Veracity test (new generation NIPT) is a robust and reliable test and can be used for singleton, twin and IVF pregnancies.
How accurate and safe is Veracity?
Veracity directly tests fetal DNA; therefore it provides the highest accuracy >99% in detection of the most common fetal aneuploidies.
It has been designed to perform with the highest standards of sensitivity and accuracy. The test is simple and straightforward.
More importantly, it is not associated with any risk of miscarriage.
PLEASE NOTE: a positive result indicates there may be a higher risk of a genetic condition being present. It does not provide a diagnosis.
This should be confirmed by amniocentesis. This will discussed with you by your medical professional.
If you have any questions about Veracity or if you unsure of which test you require, please contact the clinic for more information.
Telephone:
02830263712
Frequently Asked Questions
NIPD Genetics:VERAgene (comprehensive NIPT)
What is a non-invasive prenatal test (NIPT)
A non-invasive prenatal test (NIPT) is a test taken by a pregnant woman that will screen for genetic conditions that may be present in the fetus before birth.
The main benefit of Non-Invasive Prenatal Testing is that it is performed very early during pregnancy (10 weeks) and is more accurate that traditional screening tests currently in practice.
There are many NIPTs to check for genetic conditions such as Down Syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18) and Patau Syndrome (Trisomy 13)
Sex chromosome (X & Y) aneuploidies (chromosomal changes).
VERAgene is the only comprehensive NIPT that can simultaneously screen for:
• Common aneuploidies
• Specific clinically significant microdeletions
• 100 single gene (monogenic diseases)
Aneuploidies such as Down Syndrome are screened by many other NIPT and may be offered in NHS setting.
However, VERAgene offers microdeletions and single gene diseases that cannot be detected by another means prenatally.
Biochemical and ultrasound signs for these disorders are often not possible. In addition to this, the disorders are not associated with maternal age therefore will not be picked up by pre-natal tests aimed at a particular age group.
The 100 monogenic diseases screened by VERAgene are often very severe and therefore have a significant impact on quality of life.
These monogenic diseases may manifest as congenital anomalies, developmental delays, hearing loss and blindness. If these genetic conditions are not picked up before birth, a lot of specific testing will be necessary after birth instead of targeted treatment.
What is VERAgene (Comprehensive NIPT)?
VERAgene was introduced by NIPD Genetics in 2018 and screened for aneuploidies, microdeletions and 50 single gene diseases of autosomal recessive inheritance.
In additions to this, in January 2020. VERAgene was then expanded to screen for aneuploidies, microdeletions and 100 single gene diseases of autosomal recessive and X-linked inheritance.
VERAgene provides a comprehensive picture a pregnancy using a single test. One of the main benefits of VERAgene is that it is the only non-invasive prenatal test that can simultaneously screen for aneuploidies, microdeletions and single gene diseases
How does VERAgene (comprehensive NIPT) work?
What will the test involve?
During pregnancy cell-free fetal DNA is released from the placenta and circulates in the mother’s blood along with her own cell-free DNA. This important discovery let to the development of non-invasive prenatal tests (NIPT).
Cell-free DNA is isolated from the mother’s blood and is subsequently examined for aneuploidies and microdeletions.
In addition to this, the paternal DNA is analysed for any potential genetic mutations.
During your appointment you will be offered an ultrasound scan to date your pregnancy. The VERAgene test can be taken from 10 weeks gestation.
During the test procedure in Mourne Scan Clinic, a nurse or sonographer will take a blood sample from the mother’s arm.
This will be subsequently sent to the state-of-the-art laboratory for assessment.
A buccal swab (this is a simple swab of the inside of the mouth) will be taken from the father.
This will be sent to the state of the of the art laboratory for assessment.
The results will be sent to Mourne Scan Clinic, you will be given another appointment to discuss results. (This is usually 10 working days)
What are the conditions can be detected by VERAgene (comprehensive NIPT)
VERAgene is based on the same new technology as NIPD Genetic’s Veracity test (new generation NIPT.
VERAgene can detect:
• Down Syndrome (Trisomy 21)
• Edwards Syndrome (Trisomy 18)
• Patau Syndrome (Trisomy 13)
• Turner Syndrome
• Triple X Syndrome
• Klinefelter Syndrome
• Jacobs Syndrome
• XXYY Syndrome
• DiGeorge Syndrome
• 1p35 deletion Syndrome
• Smith-Magenis Syndrome
• Wolf-Hirschhorn Syndrome
• Cystic fibrosis
• Sickle cell disease
• Beta Thalassemia
• Tay-Sachs disease
• Gaucher disease
• Phenylketonuria
• Autosomal recessive polycystic kidney disease
• Canavan disease
• Fanconi Anemia, Type C
• Usher Syndrome, Type 1F
• Myotubular Myopathy
• Alstrom Syndrome
• Abetalipoprotinemai
• Bardet-Biedl Syndrome
• Alport Syndrome , X Linked
• Pendred Syndrome
• Familial Dysautonomia
• Joubert Syndrome
• Glutaric Acidemia Type 2A
• Maple Syrup Urine Disease, Type 1B
• Factor X1 Deficiency
(The list above does not include all the genetic conditions screened)
When can I take the VERAgene test (Comprehensive NIPT)
You can take the test as early as the 10th week of pregnancy.
How accurate and safe is VERAgene?
The cumulative risk for the fetus to be affected by one of the genetic conditions screened by VERAgene is 1 in 50. This is based on high and moderate risk pregnancies.
VERAgene directly tests fetal DNA; therefore it provides the highest accuracy >99% in detection of fetal genetic conditions.
It has been designed to perform with the highest standards of sensitivity and accuracy. The test is simple and straightforward.
More importantly, it is not associated with any risk of miscarriage.
PLEASE NOTE: a positive result indicates there may be a higher risk of a genetic condition being present. It does not provide a diagnosis.
This should be confirmed by amniocentesis. This will discussed with you by your medical professional.
Information on Panorama Testing in Ireland
What happens at a Panorama test?
This is a non-invasive prenatal test that involves a simple blood test to find out the likelihood of your baby having a particular genetic condition.
How accurate is the Panorama gender test?
The test is based off fetal DNA and the margin for error is very small. The test has more than a 99% accuracy rate.
What is a Panorama gender test?
Gender determination is included in the Panorama blood test taken from the mother.
How long does it take for Panorama test results?
Test results will take between 7-14 days depending on Bank Holidays.
Why do parents get a Panorama test?
Panorama test is a non-invasive genetic prenatal test that screens for genetic conditions. It can be taken early in pregnancy and has no effect on the baby or mother.
If you have any questions about VERAgene or if you unsure of which test you require, please contact the clinic for more information.
Telephone: 02830263712
NIPD Patient Privacy Summary
(Please refer to our privacy policy)
NIPD Genetics is accountable for processing the personal data collected when the genetic screening test is taken.
NIPD Genetics have appointed a data protection officer (DPO).
If you have any further enquiries about how your data is stored or processed, you are entitled to contact the DPO.
Email address: dpo@nipd.com
Full name of legal entity: NIPD Genetics Molecular Laboratories Limited (HE 418406)
The data which we collect about you (personal data)
NIPD Genetics: collect, use, and store some information about you such as:
• identity data (name & DOB)
• contact data (contact number & address)
• sensitive data (applicable medical/ clinical data)
NIPD Genetics: How will we use your personal data?
• to register you as a new patient on our system
• to conduct your test ( Veracity or VERAgene) and to process your results
• to contact your clinic with your results
• to invoice Mourne Scan Clinic
NIPD Genetics: How we share your personal data?
• We share your data with your referring healthcare provider, so we can notify them of your results.
• We may also share your personal data with cloud providers as we store certain information in the Cloud.
International transfers
We do not:
• Transfer
• Store
• Or process your personal data outside the European Economic Area unless your healthcare provider is located outside the European Economic Area.
Your legal rights
Under certain circumstances, you have rights under data protection laws to receive a copy of the personal data we hold about you. You have the right to erasure,(right to be forgotten) the Right to restriction of processing and the Right to make a complaint at any time to the Office of the Commissioner of Personal Data Protection.
